Lorenz C Hofbauer Selected Research

Bone Density Conservation Agents

11/2017	Sclerostin Blockade and Zoledronic Acid Improve Bone Mass and Strength in Male Mice With Exogenous Hyperthyroidism.
5/2016	Combined inhibition of the mevalonate pathway with statins and zoledronic acid potentiates their anti-tumor effects in human breast cancer cells.
1/2015	Targeting bone metabolism in patients with advanced prostate cancer: current options and controversies.
7/2011	Seizures associated with zoledronic acid for osteoporosis.
3/2002	Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts.

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Lorenz C Hofbauer Research Topics

Disease

53	Neoplasms (Cancer) 03/2024 - 12/2002
41	Osteoporosis 05/2024 - 04/2002
32	Breast Neoplasms (Breast Cancer) 02/2024 - 11/2005
25	Bone Resorption 04/2024 - 01/2002
19	Bone Diseases (Bone Disease) 01/2023 - 04/2003
19	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2004
16	Prostatic Neoplasms (Prostate Cancer) 03/2024 - 06/2011
8	Hyperthyroidism 05/2024 - 01/2015
7	Inflammation (Inflammations) 01/2023 - 11/2003
7	Rheumatoid Arthritis 01/2023 - 07/2004
6	Arthritis (Polyarthritis) 01/2023 - 03/2016
5	Vascular Diseases (Vascular Disease) 10/2015 - 09/2002
4	Iron Overload 01/2023 - 12/2016
4	Osteoporotic Fractures 12/2022 - 09/2007
4	Metabolic Bone Diseases (Osteopenia) 01/2021 - 03/2002
4	Postmenopausal Osteoporosis 01/2020 - 07/2004
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 09/2019 - 12/2011
4	Multiple Myeloma 01/2016 - 04/2003
4	Vascular Calcification 10/2015 - 08/2004
4	Thyroid Neoplasms (Thyroid Cancer) 10/2014 - 12/2004
4	Pheochromocytoma 02/2012 - 12/2002
4	Coronary Artery Disease (Coronary Atherosclerosis) 12/2005 - 03/2003
3	Insulin Resistance 12/2023 - 11/2018
3	Thyroid Diseases (Thyroid Disease) 11/2023 - 01/2002
3	Obesity 01/2023 - 01/2018
3	Diabetes Mellitus 11/2022 - 12/2011
3	Disease Progression 08/2022 - 06/2015
3	Carcinogenesis 01/2022 - 03/2012
3	Hemochromatosis (Bronze Diabetes) 01/2022 - 12/2016
3	Osteonecrosis (Kienbock's Disease) 10/2021 - 04/2013
3	Type 2 Diabetes Mellitus (MODY) 04/2014 - 12/2011
2	Iron Deficiencies 04/2024 - 01/2021
2	Periodontitis 01/2024 - 03/2012
2	Glucose Intolerance 12/2023 - 01/2021
2	Metabolic Diseases (Metabolic Disease) 11/2023 - 01/2023
2	Hypoparathyroidism 01/2023 - 11/2021
2	Osteoarthritis 12/2022 - 11/2021
2	Hip Fractures (Intertrochanteric Fractures) 12/2022 - 01/2020
2	Hypothyroidism 09/2022 - 01/2019
2	Vitamin D Deficiency 08/2022 - 01/2020

Drug/Important Bio-Agent (IBA)

23	Diphosphonates (Bisphosphonates)IBA 09/2022 - 03/2002
23	OsteoprotegerinIBA 01/2019 - 08/2002
17	GlucocorticoidsIBA 01/2023 - 11/2003
16	Denosumab FDA Link 12/2022 - 01/2009
15	Zoledronic Acid (Zometa)FDA Link 09/2022 - 08/2009
14	LigandsIBA 01/2023 - 08/2002
13	CytokinesIBA 12/2022 - 01/2002
12	Proteins (Proteins, Gene)FDA Link 02/2024 - 07/2004
11	CalciumIBA 01/2023 - 09/2005
9	Mevalonic Acid (Mevalonate)IBA 01/2022 - 03/2012
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2003
8	Hormones (Hormone)IBA 08/2021 - 10/2014
7	IronIBA 04/2024 - 03/2011
7	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 03/2024 - 02/2014
7	RANK LigandIBA 01/2018 - 01/2002
7	Messenger RNA (mRNA)IBA 03/2016 - 01/2002
6	Estrogens (Estrogen)FDA Link 11/2022 - 08/2002
5	Thyroid HormonesIBA 11/2023 - 10/2015
5	Vitamin D FDA LinkGeneric 01/2023 - 06/2010
5	romosozumabIBA 12/2022 - 10/2016
5	Estrogen ReceptorsIBA 06/2019 - 04/2008
5	Bone Density Conservation AgentsIBA 11/2017 - 03/2002
5	Monoclonal AntibodiesIBA 10/2016 - 01/2009
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2013 - 12/2002
4	Atorvastatin (Lipitor)FDA Link 03/2024 - 02/2014
4	Glycoproteins (Glycoprotein)IBA 02/2024 - 04/2002
4	MicroRNAs (MicroRNA)IBA 06/2022 - 01/2020
4	AndrogensIBA 11/2020 - 08/2002
4	Aromatase InhibitorsIBA 10/2020 - 08/2017
4	AntibodiesIBA 10/2020 - 12/2002
4	Teriparatide (Parathar)FDA Link 01/2019 - 06/2010
4	Insulin (Novolin)FDA Link 11/2018 - 09/2007
4	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 01/2008 - 08/2002
3	Parathyroid Hormone (Parathormone)IBA 01/2023 - 04/2014
3	Tartrate-Resistant Acid PhosphataseIBA 01/2023 - 05/2009
3	Glucose (Dextrose)FDA LinkGeneric 09/2022 - 11/2018
3	Neuropilin-2IBA 01/2022 - 01/2020
3	Phosphotransferases (Kinase)IBA 09/2019 - 11/2013
3	Tamoxifen FDA LinkGeneric 06/2019 - 08/2017
3	Alendronate (Alendronate Sodium)FDA LinkGeneric 11/2018 - 05/2007
3	Phosphates (Orthophosphate)IBA 11/2017 - 02/2014
3	Epidermal Growth Factor (EGF)IBA 03/2016 - 12/2004
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2012 - 08/2004
3	TNF-Related Apoptosis-Inducing LigandIBA 02/2012 - 08/2004
3	deoxypyridinolineIBA 08/2009 - 11/2003
2	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 05/2024 - 01/2021
2	Simvastatin (Zocor)FDA LinkGeneric 03/2024 - 12/2015
2	Transferrin Receptors (Transferrin Receptor)IBA 01/2024 - 01/2023
2	Blood Glucose (Blood Sugar)IBA 12/2023 - 11/2023
2	LipidsIBA 08/2023 - 01/2023
2	InterleukinsIBA 01/2023 - 04/2006
2	MineralsIBA 01/2023 - 10/2009
2	Drinking WaterIBA 01/2023 - 11/2017
2	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2023 - 11/2017
2	Hyaluronic Acid (Hyaluronan)IBA 12/2022 - 06/2012
2	CollagenIBA 11/2022 - 03/2016

Therapy/Procedure

42	Therapeutics 01/2023 - 11/2003
3	Castration 01/2022 - 01/2015
3	Drug Therapy (Chemotherapy) 05/2021 - 10/2014
2	Ligation 12/2022 - 08/2004